I did my B.Sc (Chem Hons, 2001) and M.Sc. in Chemistry(2003) from Calcutta University. By that time I had qualified CSIR NET (Dec 2002) and GATE (Feb 2003, AIR 6th, 99.8 percentile). Then I have joined Saha Institute of Nuclear Physics (2003) under the guidance of Prof. Samita Basu and completed my Ph.D on photochemistry by Dec 2008. Initially I had joined as lecturer in Jadavpur University in Dec 2008 but later then I have joined Presidency College in 2009 as an Asst. Professor in Chemistry. Finally I had joined Presidency University on 2013.
In Presidency College (and now Presidency University) I teach bio-inorganic chemistry and crystal field theory in MSc classes.I generally guide students in PG 2 practical classes. In BSc classes we have to take different sections at different times.
Here we have to undertake MSc projects and I generally guide these students with photophysical studies of different types of molecules using fluorescence with a special interest in medium dependence and some biophysical works (till now). M.Sc Students with good aptitude for research can publish papers during their MSc project too.
Ph.D. in Photochemistry (2003-2009): Research carried out in Saha Institute of Nuclear Physics, Kolkata, INDIA; registered from, Jadavpur University, Kolkata. Thesis title ‘INTERACTIONS OF QUINONES WITH DNA BASES: A LASER FLASH PHOTOLYSIS AND MAGNETIC FIELD EFFECT STUDY’. Advisor: Prof. Samita Basu, Senior Professor at Saha Institute of Nuclear Physics, Chemical Sciences Division, Kolkata.
Master of Science in Chemistry (Inorganic Special) (2001-2003), 1st Class (Rank 2nd, recipient of Sadhan Basu memorial award), Calcutta University.
Bachelor of Science (Chemistry Hons.) (1998-2001), 1st Class, Presidency College, Kolkata.
Qualified Graduate Aptitude Test in Engineering (GATE-2003) : All India Rank 6th., 99.8 percentile
Qualified National Eligibility Test (CSIR NET-JRF, Dec 2002), conducted by Council for Scientific & Industrial Research and University Grants Commission (CSIR & UGC), New Delhi, INDIA.
Rank 1st in Public Service Commission for faculty recuitment in Goverment Colleges in WB, 2008.
Natural polyphenols have long been used for the prevention and treatment of several disorders due to their antioxidant, anti-inflammatory, cytotoxic, antineoplastic, and immune modulatory effects discussed in the literature, which have led to their recognition as potential nutraceuticals. They are reported to be effective against viruses,Bacteria,Fungus, Cancerous cells, Obesity, Radiation induced damage (our findings) and Ulcers.
Side by side newer researches are emerging to check their efficacy in cosmetic industry and its gastroprotective efficacy.One of the problems regarding the use of polyphenolic compounds is their low bioavailability. Different types of formulations have been designed for the improvement of bioavailability of these compounds, nanoformulations, chemical modicifications, micellar encapsulations being the most notable ones. Today, several nanoformulations are designed for delivery of polyphenolic compounds, including nanosuspensions, solid lipid nanoparticles, liposomes, gold nanoparticles, and polymeric nanoparticles, which have resulted in better intracellular concentration of polyphenols, slow and sustained release of the drugs, and improvement of proapoptotic activity against tumor cells. In a nutshell these can optimize the bioefficacy of these natural drugs.
I intend to modify the administration mode of flavonoids and check the change in efficacy of these nutraceuticals.
The possibilities are:
Encapsulation in micelles (synthetic polymer micelles or protein micelles) or liposomes,
Pegylation or preparation of Nanocomposites (with chitosan, for eg) or Nanoparticulate pharmaceutical drug delivery systems
Success of these work will give a knowledge of using dietary flavonoids as potential medicines in several aspects. This will prevent additional hazards from newly synthesized molecules.
After flavonoid modification or encapsulation, I perform some biological assays to ascertain their biogical efficacy.:
I am looking for highly motivated NET qualified students with good academic track record to pursue PhD in my lab. Interested candidate may send their application with CV to me through email adity.chem@presiuniv.ac.in.
Those who are interested to work as post-doctoral fellow as DST-NPDF, they may also apply.
Photophysical and photochemical studies with different types of small molecules and also biologically significant molecules (current work) using fluorescent techniques in different media. Photophysical Studies of molecules in different micellar medium. Biophysical Chemistry using spectroscopic tools with different types of molecules. Spectroscopy Of biologically relevant fluorophores In confined media.
I have completed one DST-SERB, two UGC and one WBDST major research projects
Two students have completed their PhD thesis under my supervision. My first scholar Priti Sengupta is now pursuing her post doc in Poland. Two more are pursuing their PhD at present.
Undergraduate Level: college/University/ Institute/ No. Of years/ Pass, Hons:
(i) Part-time lecturer for six months in “Sarojini Naidu College for women” under Calcutta University, teaching both Chemistry Hons and pass. (2007)
(ii) Full time lecturer in Jadavpur University (Dec 2008-June 2009).
(iii) Full time lecturer in Presidency College (June 2009-April 2013)
(iv) Full time lecturer in Presidency University (April 2013-till date).
Post Graduate Level: Name of Univ./ College
(i) Guest Lecturer in Scottish Church College for Post Graduate Special Paper (PG 2, Inorganic) for one semester (2008).
(ii)Full time lecturer in Jadavpur University (Dec 2008-June 2009).
(iii) Full time lecturer in Presidency College (June 2009-April 2013)
(iv) Full time lecturer in Presidency University (April 2013-till date).
Besides supervising our own M.Sc students for their projects I have guided two students from different institutes:
- Chhandak adhikari, Department of Chemistry, NIT Rourkela.
Interaction of small phenolics with cyclodextrins (May 2016-July 2016).
- Kaushik Mondal, Department of Chemistry, IIT Guwahati.....
SPECTROSCOPIC STUDIES OF THYMOL—A PHENOLIC COMPOUND ( May 2014-July 2014)
- Arnab Chatterjee, VIT university, Vellore.....
Fluorescent Behavior of SMALL PHENOLIC COMPOUNDS (Dec 2013 - May 2014).
EDITOR:
1. Member of editorial board of Journal of Chemistry and Applied Biochemistry.
Membership of professional bodies
Life member of
(1) Indian Photobiology Society, Jadavpur, Kolkata – 700 032
(2) Indian Society for Surface Science and Technology, Jadavpur, Kolkata – 700 032
(3) Indian Physical society.
(4) Indian Chemical Society.
(5) ISRAPS
- “Inhibition of Human Colorectal Cancer by a Natural Product 7?Acetylhorminone and Interactions with BSA/HSA: Multispectral Analysis and In Silico and In Vitro Studies”, Sourav Pakrashy, Souvik Chakraborty, Sounik Manna, Juli Nanda Goswami, Biswajit Bhattacharya, Franziska Emmerling, Jishu Mandal, Sourav Misra, Sujata Maiti Choudhury, Mohammad K. Okla, Adity Bose, Pawan Kumar Maurya, Anjoy Majhi,* and Malay Dolai*, ACS Appl. Bio Mater. 2024, In press. (IF= 4.7)
- “Interaction of a new triazole compound with Serum albumins and Proteolytic enzyme Bromelain by Steady state fluorescence and Molecular docking techniques”, Sourav Misra, ........... Adity Bose* & Anjoy Majhi*. Indian Journalof Biochemistry & Biophysics, 61 (May 2024) 305-313.
“Milk protein-based carrier system for encapsulation of dietary polyphenol rutin: Molecular-level interactions and enhanced bioactivities”, Priti Sengupta,............, Adity Bose*, Kamalika Sen*, Journal of Molecular liquids 391 (2023) 123233. (IF = 6.0)
“A pH-driven method for liposomal encapsulation of dietary flavonoid rutin: Sustained release and enhanced bioefficacy”, Priti Sengupta, .........., Adity Bose*, Kamalika Sen*. Food Bioscience 52 (2023) 102392.(IF = 5.2)
- “Ni-sinapic acid nanocomposite in the selective sensing of permanganate ions”, Prasenjit Mondal, Pritam Singh, David Morgan, Adity Bose*, Kamalika Sen*, Journal of Photochemistry & Photobiology, A: Chemistry, 437 (2023) 114458. (IF= 4.3)
- “Identification of best working concentration and medium of Sinapic acid to ameliorate UVB induced peripheral blood mononuclear cell death”, Prasenjit Mondol, Adity Bose*, Sarmishtha Chanda*, Stem Cell Research International, 5 (1) (2022) 34-45.
“Effect of a Metal Ion in Modulating the Binding Interaction of a Dietary Flavonoid with Bovine Serum Albumin and DNA: A Spectroscopic and Theoretical Approach”, Priti Sengupta, ...........Nitin Chattopadhyay, Kamalika Sen, Adity Bose*, ACS Food Science and Technology, 2 (2022), 114-124. (IF = 2.36)
- “Liposomal Encapsulation of Phenolic Compounds for Augmentation of Bio-Efficacy: A Review’. Priti Sengupta, Adity Bose*, Kamalika Sen*, Chemistry Select, 6 (2021) 1-18. (IF = 2.1)
“Biophysical and theoretical studies of the interaction between a bioactive compound 3,5-Dimethoxy-4-hydroxycinnamic acid with Calf thymus DNA”, Prasenjit Mondal, ............ Sutapa Saha, Adity Bose*, Spectrochimica Acta A, 9, 245 (2021) 118936-118947. (IF = 4.4)
“Green Synthesis of Silver and Palladium Nanocomposites: A Study of Catalytic Activity towards Etherification Reaction”, Pritam Singh, Mita Halder, Santanu Ray, Adity Bose, Kamalika Sen, Materials Advances, 1 (2020) 2937-2952. (IF = 5.0)
- “Evaluation of bioavailability of rutin in different solvents by rutin-albumin interaction and selection of effective dose to ameliorate radiation induced cytotoxicity in human peripheral blood mononuclear cells”, Priti Sengupta, ...............Sarmishtha Chanda, Adity Bose* J. Herbal Medicine, 21 (2020) 100322-100331. (IF = 2.3)
“Multi-spectroscopic and Computational Evaluation on the Binding of Sinapic Acid and its Cu (II) Complex with Bovine Serum Albumin”, Priti Sengupta, Uttam Pal, Prasenjit Mondal, Adity Bose*, Food Chemistry, 301 (2019) 125254-125263. (IF = 8.8)
“Binding interactions of Quercetin and its Cu(II) complex with serum albumins: a spectroscopic overview’, Prasenjit Mondal, Adity Bose*, Bioimpacts, 9(2) (2019) 115-121.
Encapsulation of Thymol in cyclodextrin nano-cavities: A multi spectroscopic and theoretical study, Adity Bose*, Priti Sengupta,,............ Kamalika Sen, Spectrochim Acta A, 208 (2019) 339-348. (IF = 4.4)
- “Investigation on the Interaction of Rutin with Serum Albumins: Insights from Spectroscopic and Molecular Docking Techniques”, Priti Sengupta, Pinky Saha Sardar, Pritam Roy, Swagata Dasgupta, Adity Bose*, J. Photochem. Photobiol B., 183 (2018) 101-110.
- “A phenolic acid based colourimetric ‘naked-eye’ chemosensor for the rapid detection of Cu(II) ions”, Priti Sengupta, Aniruddha Ganguly, Adity Bose*,Spectrochim. Acta Part A, 198 (2018) 204-211.
- “Photoacidic behavior of small phenolics in micellar media” Adity Bose*, Dibyangana Parbat, Moumita Mukherjee, Pinki Saha Sardar, Sanjib Ghosh, Spec lett., 50 (2017) 81-87.
- Binding studies of serum albumins with an anticancer drug 6-Mercaptopurine: a spectroscopic analysis” Priti Sengupta, Adity Bose*, J. Ind. Chem. Soc. 93 (2016) 1243-1251.
- “Experimental techniques used to decipher binding studies of different organic molecules with serum albumins” Adity Bose*, Res & Rev: J. Chemistry, 5 (2016) 86-88 (Editorial).
- “Interaction of tea polyphenols with serum albumins: A fluorescence spectroscopic analysis” Adity Bose*, J. Lumin, 169 (2016) 220-226.
- · “Effect of phosphate group in switching off electron transfer in different media” Adity Bose* and Samita Basu, J. Mol. Liq., 191 (2014) 92-99.
- · “Electron transfer and hydrogen abstraction in biologically relevant systems”; Brotati Chakraborty, Adity Bose and Samita Basu, Selectivity control and fine tuning in high energy chemistry (2011) 93-116.
- · “Interaction of quinones with three pyrimidine bases: A laser flash photolysis study”- Adity Bose and Samita Basu, J. Lumin, 129 (2009) 1385-1389.
- · “Medium-dependent interactions of quinones with Cytosine and Cytidine: A laser flash photolysis study with magnetic field effect”- Adity Bose and Samita Basu, Biophysical Chemistry, 140 (2009) 62.
- · “Role of sugar in controlling reaction pattern: A comparative study with adenine and 2’-deoxyadenosine”- Adity Bose (neé Chowdhury) and Samita Basu, J. Photochem. Photobiol. A: Chemistry, 201 (2009) 197.
- “Laser flash photolysis and magnetic field effect studies on the interaction of uracil and its derivatives with menadione and 9, 10-anthraquinone”-Adity Bose and Samita Basu, J.Phys.Chem. A, 112 (2008) 12045.
- · “Role of sugar in controlling reaction pathways: A study with thymine and thymidine”- Adity Bose, Achintya K. Sarkar and Samita Basu, J. Lumin, 129 (2009) 1186-1191.
- “Magnetic field effect: an efficient tool to investigate the mechanisms of reactions using laser flash photolysis technique”- Samita Basu, Adity Bose and Debarati Dey. Proceedings of “International Conference of magnetic materials”, Dec 2007, Ed. A. Ghoshray, B. Bandyopadhyay, American Institute of Physics.
- · “Interaction of 9,10-anthraquinone with adenine and 2'-deoxyadenosine”- Adity Bose, Achintya K. Sarkar and Samita Basu, Biophysical Chemistry 136 (2008) 59.
- “Laser flash photolysis and magnetic-field-effect studies on interaction of thymine and thymidine with menadione: role of sugar in controlling reaction pattern”- Adity Bose, Debarati Dey and Samita Basu, Sci. Technol. Adv. Mater, 9 (2008) 024205.
- · “Interactions of Guanine and Guanosine hydrate with Quinones: A Laser flash photolysis and magnetic field effect study”- Adity Bose, Debarati Dey and Samita Basu, J.Phys.Chem. A, 112 (2008) 4914.
- · “Magnetic field effect on photoinduced electron transfer between [Cu(phen)2]2+ and DNA”- Debarati Dey, Adity Bose, Nikhil Pramanik and Samita Basu, J.Phys.Chem. A, 112 (2008) 3943.
- · “Dibenzo [a,c] phenazine: a polarity insensitive hydrogen bonding probe”-Debarati Dey, Adity Bose, Dhananjay Bhattacharyya, Samita Basu and Shyam Sundar Maity, Sanjib Ghosh, J.Phys.Chem. A, 111 (2007) 10500.
- · “Magnetic field effect on photoinduced electron transfer between Dibenzo[a,c]phenazine and different amines in acetonitrile-water mixture”-Debarati Dey, Adity Bose, Manas Chakraborty and Samita Basu, J. Phys. Chem. A, 111 (2007) 878.
- · “Structure dependent switchover of reaction modes: A laser flash photolysis and magnetic field effect study”-Adity Bose, Debarati Dey and Samita Basu, J. Photochem. Photobiol. A: Chemistry, 186 (2007) 130.
- “Interactions between 9,10 –anthraquinone and aromatic amines in homogeneous and micellar media: A laser flash photolysis and magnetic field effect study”-Adity Chowdhury and Samita Basu, J. Lumin. 121 (2006) 113.
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Presidency University Students Corner