
Soma Saha
Assistant Professor
About-
My Research Interest
My research work focuses in the studies of stochastic processes in chemical and biological systems as well as soft condensed matter. A stochastic process is destined to vary in a random manner indexed by time. Some areas of my interest include enzyme catalysis and inhibition, early-stage bacterial photosynthesis, DNA escape, force unfolding of proteins etc. These physicochemical processes when explored at the molecular level (single or few molecules), are indeed guided by intrinsic fluctuations or randomness. To understand them, we design mathematical techniques and construct analytical models. Our studies are further corroborated with sophisticated experimental results.
My Teaching Interest
I am a physical chemist. My teaching interests span the areas of physical chemistry along with the applications of computer language and useful softwares.
Qualifications+
Ph.D: Indian Institute of Technology Madras, 2013 Area of Research: Theoretical Physical Chemistry
M.Sc.: Chemistry; Visva-Bharati, 2006 Physical Chemistry Specialization
B.Sc.: Chemistry (Hons.); Visva-Bharati, 2004
Biography+
Research / Administrative Experience+
I was a Research Associate in the Dept. of Chemical Engineering at CSIR-National Chemical Labortory, Pune in 2014 and my work focused on the computational model of skin.
Teaching / Other Experience+
1. National Institute of Technology Warangal
Prior to joining Presidency University I gained teaching experience from National Institute of Technology Warangal (2015-2016) where I taught the following courses.
M.Sc. Courses
Quantum Chemistry, Symmetry and Group Theory Physical Chemistry Laboratory Inorganic Chemistry Laboratory Analytical Chemistry Laboratory
B.Tech. Courses
B.Tech. (I) Chemistry (Theory and Laboratory)
2. Presidency University
Since 2018 after joining Presidency University, I taught the following courses.
M.Sc. Courses
CHEM1002C: Advanced Group Theory CHEM 0903C: Kinetics (II) CHEM0703: Kinetics (I) CHEM0892: Computer Application
B.Sc. Courses
CHEM01C1 Lab CHEM02C4: Solutions and Colligative Properties CHEM02GE2 Lab CHEM0401: Chemical Kinetics (II) CHEM0491: Computer Applications GenED-6 CHEM0432: Chemical Equilibrium, Chemical Kinetics, Colligative Properties, Solutions of Electrolytes CHEM0603: Solutions, Colligative Properties and Phase Rule CHEM03C7: Phase Equilibria CHEM03GE3.1: Solutions and Phase Equilibria CHEM03SEC.1.1: IT Skills for Chemists CHEM04GE4: Kinetic Theory of Gas and Liquid CHEM0503: Chemical Dynamics CHEM05DSE2: Error Analysis
Post Graduate Supervision+
Academic Memberships+
Publications+
1. Nonrenewal Statistics in the Catalytic Activity of Enzyme Molecules at Mesoscopic Concentrations. S. Saha, S. Ghose, R. Adhikari and A. Dua, Physical Review Letters, 107, 218301 (2011).
2. Single-Molecule Enzyme Kinetics in the Presence of Inhibitors. S. Saha, A. Sinha and A. Dua, Journal of Chemical Physics, 137, 045102 (2012).
3. Stochastic Lindemann Kinetics for Unimolecular Gas-Phase Reactions. S. Saha and A. Dua, Journal of Physical Chemistry A, 117, 7661 (2013).
4. Application of Dynamic Disorder Approach to the Temperature Dependent Non-exponential Electron Transfer Kinetics in Rhodopseudomonas viridis. P. Kundu, S. Saha and G. Gangopadhyay, Journal of Statistical Mechanics: Theory and Experiment, 2019, 093501 (2019).
5. Mechanical Unfolding of Single Poly-ubiquitin Molecules Reveals Evidence of Dynamic Disorder. P. Kundu, S. Saha and G. Gangopadhyay, ACS Omega, 5, 9104 (2020).
6. Kinetics of Escape of ssDNA Molecules from α-hemolysin Nanopores: A Dynamic Disorder Study. P. Kundu, S. Saha and G. Gangopadhyay, Journal of Statistical Mechanics: Theory and Experiment, 2020, 053501 (2020).
7. Stochastic Kinetic Approach to the Escape of DNA Hairpins from an α-hemolysin Channel. P. Kundu, S. Saha and G. Gangopadhyay, Journal of Physical Chemistry B, 124, 6575 (2020).
8. An Exactly Solvable Stochastic Kinetic Theory of Single Molecule Force Experiments. P. Kundu, S. Saha and G. Gangopadhyay, Journal of Physical Chemistry B, 124, 7735 (2020).
9. Kinetics of Allosteric Inhibition of Single Enzyme by Product Molecules. P. Kundu, S. Saha* and G. Gangopadhyay, Journal of Physical Chemistry B, 124, 11793 (2020).
10. A Revisit to Turnover Kinetics of Individual Escherichia coli beta-Galactosidase Molecules. P. Kundu, S. Saha* and G. Gangopadhyay, Journal of Physical Chemistry B, 125, 8010 (2021).
11. A Minimal Kinetic Model for the Interpretation of Complex Catalysis in Single Enzyme Molecules. P. Kundu, S. Saha* and G. Gangopadhyay, Physical Chemistry Chemical Physics, 26, 463 (2024).
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